Killing kinetics of caspofungin, micafungin, and amphotericin B against Candida guilliermondii.

نویسندگان

  • Emilia Cantón
  • Javier Pemán
  • Macrina Sastre
  • Mónica Romero
  • Ana Espinel-Ingroff
چکیده

Amphotericin B (AMB), micafungin, and caspofungin MICs, minimal fungicidal concentrations, and time-killing curves were determined in the presence and absence of 10% inactivated serum. AMB was the only agent with consistent killing activity (time required to achieve 99.9% of growth reduction was 2.1 to 3.2 h). The presence of serum enhanced caspofungin activity but lowered those of micafungin and AMB.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 50 8  شماره 

صفحات  -

تاریخ انتشار 2006